15 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... anti-synthetase syndrome ... after 2 years of treatment ... #Myositis #diagnosis ... #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune ... (interstitial lung ... acro-osteolysis, myositis ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... disorder (Cardiac, pulmonary ... Lack of UMN/LMN signs ... necrotizing myopathy • Autoimmune ... #Differential #Diagnosis
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANAAutoimmune ... , Myositis, Mixed ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Summary Autoimmune ... Renal Syndromes ... sparing of the lung ... #management #treatment
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
• Mounier-Kuhn syndrome ... signs of chronic ... in the adjacent lung ... of the affected lung ... mycobacteria Treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment ... #Rheumatology #
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
autoimmune-mediated ... • Or brainstem syndromes ... Signs and symptoms ... Multiple Sclerosis Treatment ... management #neurology #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... disease • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune ... #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... RP-ILD), dermato-rheumatologic ... Gottron sign) ... • Shawl sign • ... #rheumatology #