267 results
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
: Distributive shock ... line for septic shock ... ), Cardiogenic shock ... , Shock where ↑ ... Reflex bradycardia Dobutamine
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Shock and Vasoactive ... and etiology of shock ... Ino-Dilators: Dobutamine ... Nesiritide 3) Treat shock ... #Vasopressors #shock
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... in refractory shock ... in setting of shock ... Methemoglobinemia • Dobutamine ... - Cardiogenic shock
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
Increase SVR Dobutamine ... pharmacology #comparison #shock
Clinical Management for Three Common Causes of Shock 
HEMORRHAGIC SHOCK
 • Ensure adequate ventilation and oxygenation.
Common Causes of Shock ... HEMORRHAGIC SHOCK ... CARDIOGENIC SHOCK ... 0.5 ug/min) and dobutamine ... SEPTIC SHOCK
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
first agent in shock ... line in septic shock ... SVR Inotropes Dobutamine
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
& Cardiogenic Shock ... function tests if shock ... inotrope (usually dobutamine ... with cardiogenic shock ... Checklist #CHF #Shock
Receptor actions of sympathomimetic and dopaminergic agents.
Adrenaline (epinephrine) 
Noradrenaline (norepinephrine) 
Isoprenaline 
Dopamine 
Dopexamine 
Dobutamine 

#Pharmacology #Vasopressors
Dopexamine Dobutamine
Inotropic agents in current use for the treatment of heart failure 
#heartfailure
#cardiology
#ionotropes
#epinephrine #norepinephrine #dopamine #dobutamine
norepinephrine #dopamine #dobutamine
Vasopressors - Charted by Vasoconstriction, Vasodilation, and Inotropy
 - Dobutamine
 - Milrinone 
 - Vasopressin
 -
and Inotropy - Dobutamine