14 results
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... This drug class ... #Pharmacology #Management ... #Diabetes #DM2 ... #Endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... #Pharmacology # ... Medications #DM2 ... #Diabetes #Endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
(EuDKA) SGLT2 Inhibitors ... Significant Adverse Drug ... level < 200 mg/dL Pathophysiology ... EuDKA #diagnosis #management ... #endocrinology
Bisphosphonates for Osteoporosis Treatment or Prevention 

Bisphosphonates are common medications used in the treatment and prevention
There are 4 drugs ... are a variety of dosing ... Schedule #Frequency #Pharmacology ... #Endocrinology ... #Osteoporosis #Management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly: frontal bossing ... malignancy Pathophysiology ... pachydermoperiostosis, drugs ... #Endocrinology ... #Treatment #Pathophysiology
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Xanthine oxidase inhibitor ... chemotherapy Dosing ... : 100 mg/m2/dose ... hypersensitivity Drug ... #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... immune deficiency, Drugs ... Etoposide/VP16 (100 mg/m2 ... Anti-IFN-y and JAK inhibitors ... Lymphohistiocytosis #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... necrosis factor-α inhibitors ... • Injection drug ... kidney disease • DM ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... necrosis factor-α inhibitors ... • Injection drug ... kidney disease • DM ... TB #Diagnosis #Management
IDSA Recommendations for Preventing and Treating Disseminated Mycobacterium Avium Complex in HIV-AIDS
Preventing 1st Episode of Disseminated
necessary based on drug-drug ... to Table 5 for dosing ... Prevention #Treatment #management ... #opportunistic ... infections #HIVAIDS #pharmacology