4 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Attempt if high risk ... : • Common: fever ... febrile neutrophilic ... fluid overload, PCC
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... pneumonia • Acute ... Leptospirosis Pel-Ebstein ... For every 1°F rise ... #Differential #Diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
on ABx) → Acute ... mucus, Abd pain, Fever ... immunocompromised, IBD) • ↑Risk ... Lowest Risk: Tetracyclines ... Clostridioides #Difficile #Clostridium
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
or family - Ever ... Assess functional ... event, follow ACC algorithm ... Cataract Plan for Meds ... stratification #diagnosis