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management neurology differential cns syndrome infections infectiousdiseases babesia babesiosis bee cerebritis comparison damage dermatology encephalopathy endocarditis erythematosus exposure fungal gravis
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Compatible syndrome + MRI ... toxo IgG • CNS PCR ... Syphilis • Pyogenic Abscess ... RingEnhancing #Lesions #Brain ... #causes #radiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
conditions: Autoimmune (SLE ... heart valves • MRI ... brain for cerebral ... common, Aortic root abscess ... - Infectious Diseases
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
should be based on clinical ... Antimicrobial treatment ... Imaging: - MRI ... tuberculomas, or abscesses ... Demyelinating disease
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... ruled out • Brain ... brain and/or optic ... Disorders: - SLE ... Transverse Myelitis Treatment
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... affecting the Brain ... and treatment can ... neuropathy (LHON) plus MRI ... lesions and clinical
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... Myotonic dystrophy - Brain ... Miller Fischer and PCB ... myasthenia Diagnosis ... Myasthenia #Gravis #diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
parietal lobes of the brain ... Shock, Autoimmune disease ... the underlying cause ... • Treatment of ... until cause identified
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... has five major clinical ... yeast • At risk: AIDS ... • Sinusitis • Brain ... abscess • Disseminated
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... phenomenon (16%) MSK ... Adenocarcinoma Treatment
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