11 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Erythematosus (SLE) Clinical ... Lumbar Puncture, EEG ... #neurology #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... cells per μL • Diagnosis ... should be based on clinical ... therapy Herpes Simplex ... opportunistic #InfectiousDiseases
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... (CNS) dysfunction ... Activation #Syndrome #Diagnosis ... #Rheumatology
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
A.fumigatus species complex ... HIV/AIDS, CGD) Clinical ... Rhinosinusitis, CNS ... AmphoB or Vori + systemic ... treatment #fungal #infectiousdiseases
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cryoglobulin (CG ... processes: • Systemic ... Cryofibrinogenemia Clinical ... : • + Clinical ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Non-autoimmune rheumatologic ... and CNS • Headache ... #Rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... deposit of immune complexes ... Syndrome: • Clinical ... Labs/Diagnosis: ... classification #rheumatology
Persistence of clinically relevant viruses on dry inanimate surfaces

Most common viruses persist on surfaces for days
Persistence of clinically ... 7 days Herpes simplex ... A systematic review ... viruses #surfaces #infectiousdiseases ... #diagnosis #table
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... has five major clinical ... especially the CNS ... MC: CNS CSF: • ... ) #Mycoses #InfectiousDiseases
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... Polyarthritis: • Complete ... ANA and RF (if clinical ... #testing #Rheumatology