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differential causes pediatrics alkalosis toxicology chloride genetics iem inbornerrors neonatology nephrology nicu seizures table urinary anticoagulation assessment bicarbonate citrate colchicine
Lab patterns seen in Inborn Errors of Metabolism A table of lab values compiled from UpToDate and
Inborn Errors of Metabolism ... of lab values compiled ... acute metabolic ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... #InbornErrors #Metabolism
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
inborn errors of metabolism ... , excluding complex ... presentations in acute metabolic ... #Pediatrics #Metabolism ... #Neonatology #Peds
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride • Cl- responsive metabolic alkalosis
Metabolic Alkalosis ... responsive metabolic ... Post-hypercapneic metabolic ... - resistant metabolic ... • Anion gap metabolic
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
use in cellular metabolism ... metformin binds to complexes ... via anaerobic metabolism ... includes symptoms of metabolic ... LacticAcidosis #Toxicity
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Metabolic Alkalosis ... Urinary Chloride Algorithm ... metabolic alkalosis ... - resistant metabolic ... #differential #diagnosis
Colchicine Toxicity Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly] 2-24 hrs • Severe GI distress
Colchicine Toxicity ... Renal failure • Metabolic ... acidosis • ARDS ... alopecia • Complete ... Symptoms #Signs #Diagnosis
Approach to Elevated Bicarbonate (HCO3) Risk Factors for Hypercapnea? (Hx of COPD, OSA, sedative use, CNS/muscular disorders?) (+)
for Respiratory Acidosis ... Gas) (-) Likely Metabolic ... Bicarbonate #Elevated #metabolic ... #alkalosis #algorithm ... #diagnosis
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
- Differential Diagnosis ... Algorithm Unprovoked ... Focal: Simple, Complex ... Neurocysticercosis, PML ... • Metabolic: Hypoglycemia
Citrate Anticoagulation Toxicity Hypernatremia (HyperNa): - Citrate solutions may have ↑ sodium content and should be paired
binds Mg: this complex ... mmol/L Anion-Gap Metabolic ... Acidosis: - Citrate ... impairing citrate metabolism ... Metabolic alkalosis
Causes of Hypotonic Infant (Floppy Newborn) - Differential Diagnosis Algorithm Central Nervous System - Decreased LOC, Axial
- Differential Diagnosis ... Algorithm Central ... Infection • Metabolic ... Dystrophies • Metabolic ... #Peds #Pediatrics
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