1226 results
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
maximum dose eGFR ... recommended dose eGFR ... #Metformin #CKD ... #pharmacology #
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
Patients With CKD ... , & an eGFR ≥ 30 ... evidence-based pharmacologic ... #Diabetes #CKD # ... ADA #KDIGO #eGFR
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
Staging CKD Staging ... CKD is most frequently ... function rate (eGFR ... calculating the eGFR ... #EGFR #Staging
Definitions of AKI, CKD, AKD
Acute Kidney Injury (AKI):
 • Increase in SCr by 2 50% within
Kidney Disease (CKD ... ): • GFR < 60 ... ): • GFR ≥ 60 ... /CKD • No structural ... damage #AKI #CKD
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
Creatinine: • AKI, CKD ... nephroprotective ↓ in GFR ... Cystatin C: • AKI, CKD ... hyperthyroidism ↓ eGFR
Adjusted Pain Medication Dosing based on GFR

#Renal #Dosing #Pain #Pharmacology #Opiates #CKD #Gabapentin #Table
Dosing based on GFR ... #Dosing #Pain #Pharmacology ... #Opiates #CKD #
Renal Failure Prognosis - The eGFR and proteinuria offers a general prognosis as demonstrated in the
Prognosis - The eGFR ... #CKD #EGFR #Proteinuria
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
#Medications #Pharmacology ... Renal #Impairment #CKD ... #Table #GFR #Hypoglycemics
Complications of CKD
 - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
Complications of CKD ... with stages 1-3 ([GFR ... >30 mL/min) of CKD ... clinically in CKD ... stages 4-5 (GFR
Patient factors influencing the selection Of glucose-lowering drugs Other than SGLT2i and metformin in T2D and
metformin in T2D and CKD ... cardiovascular disease: CKD ... —4 inhibitor, eGFR ... , #KDIGO2020 #CKD ... Management in CKD