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Metformin in Diabetic Kidney Disease Immediate release: • Initial 500 mg or 850 mg once daily •
Metformin in Diabetic ... maximum dose eGFR ... recommended dose eGFR ... < 30: Stop metformin ... annually if on metformin
Metformin Current Renal Dose Adjustments due to Risk of Lactic Acidosis > 60 No adjustment 45-60
Metformin Current ... 45-60 Monitor eGFR ... already taking metformin ... /ambcarerx #Metformin
The GFR Clock for Staging CKD Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... calculating the eGFR ... to remember the eGFR ... #Nephro #CKD #EGFR
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... not initiate if eGFR ... not continue if eGFR ... EricsMedicalLectures/ #Metformin
Management of Diabetes Mellitus in Patients With CKD 1. Monitor for changes in BP, serum creatinine, &
FDA recommends, metformin ... T2D, CKD, & an eGFR ... per 1.73 m2 with metformin ... CKD #ADA #KDIGO #eGFR ... #Insulin #metformin
Diabetes Combination Tablets - Estimated A1c Lowering Metformin + DPP4 • Janumet (metformin + sitagliptin) •
A1c Lowering Metformin ... DPP4 • Janumet (metformin ... • Jentadueto (metformin ... • Kombiglyze (metformin ... saxagliptin) Metformin
Interpreting Kidney Biomarkers ↑ Creatinine: • AKI, CKD • Medications that lead to nephroprotective ↓ in
nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR
Renal Failure Prognosis - The eGFR and proteinuria offers a general prognosis as demonstrated in the
Prognosis - The eGFR ... #CKD #EGFR #Proteinuria
Causes of Hypomagnesemia - Differential Diagnosis Algorithm GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Hypomagnesemia - Differential ... Cetuximab and other EGFR ... in Na-KATPase, EGFR ... #Low #Causes #Differential
Patient factors influencing the selection Of glucose-lowering drugs Other than SGLT2i and metformin in T2D and
than SGLT2i and metformin ... —4 inhibitor, eGFR
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