861 results
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
Metformin in Diabetic ... maximum dose eGFR ... recommended dose eGFR ... < 30: Stop metformin ... annually if on metformin
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
Metformin Current ... 45-60 Monitor eGFR ... already taking metformin ... /ambcarerx #Metformin
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
• AKI, CKD • Medications ... nephroprotective ↓ in GFR ... • Medications ... hyperthyroidism ↓ eGFR
Diabetes Medication Choice
-Diabetes Medication Choice decision aid cards provide information on medications commonly used to treat
Diabetes Medication ... Choice -Diabetes Medication ... information on medications ... - To date only metformin ... , SGLT-i, GLP1 medications
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... calculating the eGFR ... to remember the eGFR ... #Nephro #CKD #EGFR
Oral Antidiabetics

#Diabetes #Medications #Oral #Pharmacology #Sulfonylurea #metformin
#Diabetes #Medications ... #Sulfonylurea #metformin
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Common Diabetes Medications ... • Biguanides (Metformin ... • Biguanides (Metformin ... #Diabetes #Medications
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Metformin - First ... than stopping medication ... #Metformin ... #Indications #Titration
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... not initiate if eGFR ... not continue if eGFR ... EricsMedicalLectures/ #Metformin
Diabetes Type 2 Medication Management and Titration Algorithm
- First line therapy is metformin and comprehensive lifestyle
Diabetes Type 2 Medication ... line therapy is metformin ... Diabetes #DM2 #Type2 #Medication