82 results
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
Metformin Current ... Renal Dose Adjustments ... 45-60 Monitor eGFR ... already taking metformin ... #Renal #Dosing
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
Metformin in Diabetic ... maximum dose eGFR ... recommended dose eGFR ... < 30: Stop metformin ... annually if on metformin
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
nephroprotective ↓ in GFR ... Medications that ↓ renal ... hyperthyroidism ↓ eGFR ... Biomarkers #Kidney #renal
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
recommendations in renal ... Dosing #Dosing #Renal ... Impairment #CKD #Table ... #GFR #Hypoglycemics
Renal Failure Prognosis - The eGFR and proteinuria offers a general prognosis as demonstrated in the
Renal Failure Prognosis ... - The eGFR and ... #CKD #EGFR #Proteinuria
Adjusted Pain Medication Dosing based on GFR

#Renal #Dosing #Pain #Pharmacology #Opiates #CKD #Gabapentin #Table
Dosing based on GFR ... #Renal #Dosing ... CKD #Gabapentin #Table
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
formulas are shown in Table ... Modification of Diet in Renal ... unless a patient's renal ... seen in acute renal ... CockcroftGault #EGFR
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... not initiate if eGFR ... not continue if eGFR ... EricsMedicalLectures/ #Metformin
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
FDA recommends, metformin ... T2D, CKD, & an eGFR ... per 1.73 m2 with metformin ... CKD #ADA #KDIGO #eGFR ... #Insulin #metformin
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
Renal involvement ... - 85% • Mean eGFR ... follow-up • eGFR ... TerrierBen #Renal