6673 results
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
function rate (eGFR ... calculating the eGFR ... to remember the eGFR ... @JustinBerk #Diagnosis ... #Nephro #CKD #EGFR
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR ... Kidney #renal #diagnosis
Renal Failure Prognosis - The eGFR and proteinuria offers a general prognosis as demonstrated in the
Prognosis - The eGFR ... #CKD #EGFR #Proteinuria ... Prognosis #Heatmap #Diagnosis
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
45-60 Monitor eGFR ... #Dosing #Dose #Pharmacology
Adjusted Pain Medication Dosing based on GFR

#Renal #Dosing #Pain #Pharmacology #Opiates #CKD #Gabapentin #Table
Dosing based on GFR ... #Dosing #Pain #Pharmacology
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
maximum dose eGFR ... recommended dose eGFR ... Metformin #CKD #pharmacology
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
#Medications #Pharmacology ... Impairment #CKD #Table #GFR
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... not initiate if eGFR ... not continue if eGFR ... #Metformin #Pharmacology
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
- Differential Diagnosis ... Cetuximab and other EGFR ... in Na-KATPase, EGFR ... #Differential #Diagnosis
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
accurately predict GFR ... overestimation of GFR ... used to estimate GFR ... #Diagnosis #Nephrology ... CockcroftGault #EGFR