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blood hemolysis product acidosis anemia dermatology elevation encephalopathy extravascular intravascular lactic neurology nonpalpable palpable posterior purpura reversible rheumatology transfusion transfusions
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... - Drugs (Beta lactam ... #differential # ... diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Valves, AS - HTN/Pre-eclampsia ... AIHA, Transfusion reactions ... Haptoglobin ↓ - Lactate ... Diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... - APLS • Acute ... fever • Drug reactions ... #Diagnosis #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... haptoglobin, ↑LDH, etc ... Transfusion Related Acute ... #Transfusion #diagnosis ... #management #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate ... presentations and disease ... - Compartment syndrome ... #Diagnosis #causes ... #typea #typeb #classification
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... - Acute Hemolytic ... Transfusion Related Acute ... #Transfusions #diagnosis ... #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Shock, Autoimmune disease ... Reversible course Differential ... , ADEM, Acute toxic ... #diagnosis #management ... #neurology
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