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management blood reactions anemia atlas bloodcell cvid extravascular gap globulin hemolytic hodgkins hypogammaglobulinemia immunodeficiency immunology intravascular microscopy morphology nomenclature oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... . lupus, CLL, lymphoma ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
(e.g. methotrexate ... disease, Etc. ... Unstable hemoglobin disorders ... RBC #Morphology #differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... • Anemia • Pruritis ... (NSHL) - (most common ... #diagnosis #classification ... #hematology #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... • Liver diseases ... and autoimmune hemolytic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... maculopapular rash, pruritis ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
haptoglobin, ↑LDH, etc ... maculopapular rash, pruritis ... eruptions, diarrhea, liver ... #Transfusion #diagnosis ... #management #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... Comment on type ... #diagnosis #hematology
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