9 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... thrombocytopenic purpura ... lymphoproliferative disorders ... #Causes #differential ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... , Liver disease, ... Unstable hemoglobin disorders ... RBC #Morphology #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... anemia - Splenomegaly ... deficiency • Liver ... Diagnosis #hematology ... #rheumatology #
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Normal Blood Smear ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... IgA, IgG, IgM (CVID ... changes), high MCV anemia ... Diagnosis #Causes ... #Workup #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Liver diseases ... anemia) • Systemic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
which can plug blood ... processes: • Systemic ... Skin necrosis • Purpura ... #rheumatology # ... hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
in recipient (e.g ... Causes purpura & ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... number of sites of disease ... #hematology #oncology ... #management