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bleeding blood oncology product reactions acidosis activation algorithm anemia ascites cvid elevation extravascular hemolysis hemolytic hemostasis hodgkins hypogammaglobulinemia immunodeficiency immunology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
/ Bruising - Differential ... Thrombocytopenia ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... coagulation (DIC) - HELLP ... microangiopathy: Thrombotic thrombocytopenic ... #differential # ... diagnosis #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Liver diseases ... specifically immune thrombocytopenia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
most common causes ... more than one cause ... (e.g. cirrhosis ... of underlying disease ... #Diagnosis #hepatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
manifestations: from easy bruising ... leukopenia, anemia, and thrombocytopenia ... • Liver function ... #Diagnosis #Management ... #Hematology #Rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... von Willebrand syndrome ... defects in the common ... discern these causes ... #Diagnosis #Hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
most common causes ... presentations and disease ... - Compartment syndrome ... #Diagnosis #causes ... #typea #typeb #classification
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Easy or unusual bruising ... Most common cytopenia ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
) Classification ... Immunohistochemical studies (to differentiate ... number of sites of disease ... #hematology #oncology ... #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
haptoglobin, ↑LDH, etc ... severe thrombocytopenia ... eruptions, diarrhea, liver ... #Transfusion #diagnosis ... #management #hematology
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