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blood reactions rheumatology acidosis activation aflp algorithm coagulation dermatology dili disseminated druginduced elevation fatty hodgkins injury intravascular lactate lactic lymphoma
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
acid metabolism products ... rapidly develops (DIC ... , ascites, jaundice ... infiltration) Differential ... #Pregnancy #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... disease, Hepatic ... . ascites), Chronic ... #Algorithm #hepatology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
Ascites - Diagnostic ... most common causes ... (e.g. cirrhosis ... of underlying disease ... #Diagnosis #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Severe Liver ... Disease: - Impaired ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
complication: DIC ... disease 2. ... #Diagnosis #Management ... #causes #treatment ... #nephrology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
thrombocytopenia • Liver ... Fibrin degradation products ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... pain, dark urine, DIC ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... presentations and disease ... - Compartment syndrome ... #Diagnosis #causes ... #typea #typeb #classification
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... Tetracyclines etc ... osteoarticular and skin disease ... diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... haptoglobin, ↑LDH, etc ... eruptions, diarrhea, liver ... #Transfusion #diagnosis ... #management #hematology
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