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algorithm injury liver management saag albumin cholangitis conjugated dili druginduced gap globulin gradient hepatomegaly hodgkins hypertension jaundice oncology pbc portal
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... hepatitis) - 80% ... Fitz-Hugh-Curtis syndrome ... Failure, Pancreatic, Biliary ... Diagnosis #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Metastases • Lymphoma ... Hemochromatosis • Wilson's Disease ... • Budd-Chiari Syndrome ... Cirrhosis #Hepatomegaly ... #Causes #Hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
(Budd-Chiari syndrome ... 14 percent) #Diagnosis ... #Differential # ... Hepatology #Cirrhosis ... #Causes
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 Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
reactions, hematoma, pulmonary ... , hepatitis, hepatic ... , sarcoidosis, lymphomas ... #diagnosis #conjugated ... #unconjugated #differential
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Clues to non-cirrhotic ... /acute hepatitis ... pregnancy • Primary biliary ... #Diagnosis #causes ... #hepatology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
Ascites - Diagnostic ... (e.g. cirrhosis ... of underlying disease ... #workup #Differential ... #Diagnosis #hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... - Hepatic: • Cirrhosis ... • Infiltrative disease ... failure • Primary biliary ... #Hepatology #causes
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Diagnosis High ... - Alcoholic hepatitis ... Tuberculosis - Biliary ... syndrome - Ascites ... #Diagnosis #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... - Cirrhosis ... - Alcoholic hepatitis ... #Causes #diagnosis ... hepatology #SAAG
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... bile ducts Differential ... Viral hepatitis, ... Endocrinopathy, Lymphoma ... #workup #hepatology
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