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rheumatology lupus sle systemic allergy cns common cvid dermatology hypogammaglobulinemia immunodeficiency immunology macrophage mds myelodysplasia myelodysplastic neurology oncology sapho syndromes
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... #cerebritis #diagnosis ... #management #treatment
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Diagnosis Framework ... 2nd pass = Chronic ... : • Mast cell ... activation syndrome ... #Diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Syndrome (MAS) ... Classified among the secondary ... #Syndrome #Diagnosis ... #Management #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... with Lupus: • Chronic ... B-cell activation ... #Diagnosis #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... may take 6 to 8 ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... Rule out other causes ... Tetracyclines etc ... osteoarticular and skin disease ... diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Marrow Failure • Chronic ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
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