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anemia hemolytic vasculitis agglutinin atlas bloodcell cryofibrinogenemia cryoglobulinemia erythematosus extravascular hemolysis intravascular lupus microscopy morphology myopathy nomenclature rbc red sle
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... . lupus, CLL, lymphoma ... cold agglutin disease ... #differential # ... diagnosis #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... autoimmune hemolytic ... Malignant lymphoma ... RBC #Morphology #differential ... #diagnosis #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... diseases: - 10% ... Type III Often Secondary ... #classification ... #rheumatology #
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
with autoimmune ... • Negative causes ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Syndrome (CAS): ... disorder or lymphoid ... pts) Differential ... hemolytic #anemia #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... rheumatologic diseases ... with Lupus: • Chronic ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... tract, and often causes ... Serologies for Cryoglobulins ... #diagnosis #rheumatology ... #classification
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... - Differential ... statins - probably caused ... #rheumatology # ... differential #diagnosis
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