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algorithm systemic dermatology pruritus agglutinin anemia autoimmune cold comparison cryofibrinogenemia cryoglobulinemia erythematosus focal hemolytic hodgkins lad leukemia localized lupus lymphadenopathy
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... • Autoimmune diseases ... Type III Often Secondary ... #classification ... #rheumatology #
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
• Infection (e.g ... • Kikuchi Disease ... Tularemia • Secondary ... #Causes #Hematology ... #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Pruritus: (focal or generalized ... translocation • Types: Classification ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis ... Creatinine & BUN: • Chronic ... : • Lymphoma ... Myelodisplastic syndrome ... #dermatology #Differential
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... • Negative causes ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
: • Lymphoma ... Myelodisplastic syndrome ... #systemic #generalized ... #dermatology #Differential ... #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... tract, and often causes ... differential #diagnosis ... #rheumatology # ... classification
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... AIHA Primary Secondary ... Cold Agglutinin Syndrome ... younger pts) Differential ... hemolytic #anemia #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... with Lupus: • Chronic ... #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... • Tumor lysis syndrome ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
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