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diagnosis dermatology rheumatology systemic algorithm lupus management primary pruritus sle vasculitis acidosis activation alopecia ascites atlas basics cns cryoglobulinemia cryoglobulins
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... Lumbar Puncture, EEG
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Systemic and Primary Causes ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #dermatology #Differential
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... halt nail growth (e.g ... • Nephrotic syndrome ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Diffuse and Focal) Differential ... • Loose anagen syndrome ... to Skin Disease ... #Differential # ... Diagnosis #Algorithm #causes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... • Malignancy (e.g ... . hematologic) ... vein thrombosis Hematologic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... Systemic lupus erythematosus ... Hepatosplenomegaly and generalized ... systemic lupus erythematosus ... Diagnosis #Management #Hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Myelodisplastic syndrome ... #Pruritus #secondary ... #systemic #generalized ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... • Autoimmune diseases ... Type III Often Secondary ... systemic lupus erythematosus ... diagnosis #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... tract, and often causes ... ischemia - Skin: erythematous ... systemic lupus erythematosus ... #classification
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... (e.g. cirrhosis ... carcinomatosis, HF, etc ... of underlying disease
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