6 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... . sickle cell disease ... #Causes #differential ... #diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Diagnosis Algorithm ... Non-lmmune: • HELLP Syndrome ... Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Diagnosis Secondary ... Myelodysplastic syndrome ... myeloid leukemia ... #Diagnosis #Causes ... #hematology #secondary
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... CausesAnemia ... Cell Leukemia ... #diagnosis #hematology ... #oncology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology