13 results
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... • Malignancy Infectious ... Pulmonary Disease Neurologic ... Myasthenia Gravis Pharmacologic ... Syndrome #Chronic
Myocarditis 

5 Principles of
Myocarditis:
1. Build clinical suspicion
2. Decide on EMBx
3. Manage acute cardiac injury
4. Manage chronic
Rash, Myalgias, Fatigue ... Fulminant: - Acute HF ... Pericarditis, Tamponade EKG ... Low voltage Treatment ... diagnosis #management #cardiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
response preceding infection ... Electrodiagnostic studies - EMG ... Treatment: • Plasmapheresis ... diagnosis #management #treatment ... #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... - Generalized fatigue ... Serologic and EMG ... precipitated by: Drugs, infection ... diagnosis #management #neurology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... Differential Diagnosis: Infection ... sepsis), PE, DAH, CHF ... diagnosis #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Preeclampsia, Eclampsia, Infection ... Diagnosis: • Infection ... epilepticus Treatment ... underlying cause • Treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Electrodiagnostic studies (Ex EMG ... and cauda equina TREATMENT ... Guillain #Barre #Syndrome ... diagnosis #management #neurology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Symptoms: • Fatigue ... petechiae) • Frequent infections ... • Parvovirus infection ... factors (examples: G-CSF ... #diagnosis #hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
cool extremities, fatigue ... acute coronary syndrome ... algorithm #management #cardiology ... #heartfailure #chf ... icu #clinical #pharmacology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... . extreme fatigue ... vasculitis vs infection ... of the steroid treatment ... Treatment of GCA