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Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... derangement of liver ... clinical symptoms/signs ... presence of metabolic syndrome ... magnitude of enzyme elevation
Differential Diagnosis for ST Segment Elevations
 - ACUTE STEMI 
 - PULMONARY EMBOLISM 
 - LBBB
for ST Segment Elevations ... ) - BRUGADA SIGN ... (SYNDROME) - ... SPIKED HELMET SIGN ... #STSegment #STElevation
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
manifestations of acute liver ... Hepatorenal syndrome ... abnormalities Liver ... manifestations #acute #liver ... #failure #Signs
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
End Stage Liver ... Hepatopulmonary Syndrome ... • Hepatorenal Syndrom ... (HRS) • Liver ... SBP) #ESLD #Liver
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... Enzyme Elevation ... • Gilbert's syndrome
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... SinaiBmoreIMRes #Liver ... FunctionTest #LFTs #Elevation
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... to 10-20-fold elevation ... necrosis HELLP Syndrome ... Hemolysis, Elevated Liver ... to 10-20-fold elevation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Phosphatase (ALP) Elevation ... disturbance (obstructed liver ... Highest • Bone • Liver ... Other causes of elevation ... consult ALP elevation
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... vein: Budd-chiari syndrome ... Bilirubin - +/- elevation ... • Gilbert's syndrome ... Enzyme Elevation
Signs of Chronic Liver Disease ( Cirrhosis )

#Diagnosis #Cirrhosis #Signs #Symptoms #Hepatology
Signs of Chronic ... Liver Disease ( ... Diagnosis #Cirrhosis #Signs