15 results
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
and initial management ... #Diagnosis #Management ... #Hematology #HIT ... #Heparin #Induced ... Thrombocytopenia #Algorithm
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Diagnosis Framework ... : • Vascular occlusion ... Causes: - Drug induced ... #Diagnosis #hematology ... #rheumatology #
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
- Alcohol-induced ... translocation • Types: Classification ... Diagnosis of B-Symptoms ... comparison #oncology #diagnosis ... hematology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... Drug and toxin-induced ... Pulmonary veno-occlusive ... multifactorial mechanisms Hematologic ... #Diagnosis #Differential
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... fraction < 20% Differential ... Diaqnoses: • ... #diagnosis #management ... #treatment #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Diagnosis ... • TTP, HUS and HIT ... syndrome • Warfarin-induced ... #rheumatology # ... hematology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
the more likely it ... will be clinically ... (MCTD), Drug-induced ... ANA #patterns #rheumatology ... #diagnosis #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Acrocyanosis (Cold-induced ... Mycoplasma, EBV, HIV ... younger pts) Differential ... hemolytic #anemia #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Diagnosis Framework ... • Hydralazine-Induced ... reactions, and vaso-occlusive ... #diagnosis #rheumatology ... #classification
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (SVC/IVC occlusion ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology