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diagnosis differential algorithm cardiology endocarditis macrocytosis autoimmune bone dermatology disease inclusions infectiousdiseases joint jointpain macrocytic management microcytic msk myopathy myositis
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Severe hemolytic anemia ... Sideroblastic anemia ... , Hemolytic anemia ... • Hemoglobin H Inclusion ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Increased Requirement (e.g ... #Macrocytosis #elevatedMCV ... #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... - Differential Diagnosis ... #Macrocytosis #elevatedMCV ... #Differential #Diagnosis ... #Hematology
Vascular Joint Pain - Differential Diagnosis Algorithm - Constant Pain (Ischemia) - Acute Onset -
- Differential Diagnosis ... • Vasculitis Occlusion ... • Sickle Cell Anemia ... Trauma to Vessel (dislocation ... #Orthopedics #Causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... : • Vascular occlusion ... - Hemolytic anemia ... #Differential #Diagnosis ... #hematology #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Disease Vaso-occlusive ... Differentiate from vaso-occlusive ... #differential #diagnosis ... #causes #hematology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Septic Emboli Cause ... due to vascular occlusion ... ↑ ESR, CRP • EKG ... Leukocytosis, anemia ... Treat underlying cause
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
and Differential Diagnosis ... due to vascular occlusion ... ↑ ESR, CRP • EKG ... Leukocytosis, anemia ... Treat underlying cause
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... RP-ILD), dermato-rheumatologic ... phenomenon INCLUSION ... statins - probably caused ... Myositis #Myopathy #rheumatology
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