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diagnosis management workup apml approach arthritis cell classification differentiation hodgkins joint lymphoma plasmacytoma solitary syndrome
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Approach to Joint Pain ... • Ligament • Bone ... the subchondral bone ... #MSK #rheumatology ... approach #workup #differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... effusions, weight gain ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hemolytic anemia • Pain ... Immunohistochemical studies (to differentiate ... anymore • Routine bone ... classification #hematology ... #oncology #management
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
proliferation can escape ... presents with pain ... obstruction X-Ray ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
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