14 results
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
manifestations of acute liver ... abnormalities Liver ... manifestations #acute #liver ... #failure #Signs ... #Symptoms #Diagnosis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... suspicious clinical symptoms ... /signs should be ... presence of metabolic syndrome ... Abnormal #Algorithm #Hepatology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
higher incidence in lung ... >heart>liver>kidney ... EBV viral load, signs ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
the setting of liver ... • Underlying liver ... hypertension • Liver ... resolution of symptoms ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... symptoms can mimic ... lymph node, or liver ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... rash) • Heart, lung ... thrombocytopenia • Liver ... #Diagnosis #Management ... #Hematology #Rheumatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... granulomas within the lungs ... heart (2-5%), liver ... #Management #Signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - 80% have fever ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... disease • Liver ... Low serum IgG level ... : • Nephrotic syndrome ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... : >3 symptoms, or ... Differentiation #Syndrome ... #management #hematology ... #oncology