10 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... Aphasia, word-finding ... seizure, primitive reflexes ... geriatrics #diagnosis #signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... WBC >100k, + lab signs ... hydration - Hyperkalemia ... TLS #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... incidental CXR finding ... : (distinct symptoms ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of UMN and LMN signs ... Increased Jaw Jerk reflex ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Evaluation and Management of Hypokalemia

Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
Evaluation and Management ... search for warning signs ... or symptoms warranting ... Most cases of hypokalemia-induced ... #Evaluation #Algorithm
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... Non-compressive Spinal Cord Causes ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology ... differential #algorithm
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... GCA #Temporal #Signs ... #Symptoms #Diagnosis ... #Management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... Signs of congestion ... acute coronary syndrome ... the determined cause ... #differential #algorithm
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms ... Myelitis #diagnosis #management ... #neurology #differential
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
inflammation -> Acid reflux ... • Boerhaave syndrome ... hormone levels cause ... pathophysiology #diagnosis #signs ... #symptoms #psychiatry