11 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... Aphasia, word-finding ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... bladder and rectal reflex ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... of normal leg reflexes ... #MSK #pathophysiology ... #signs
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... • Mutism Pathophysiology ... • Examine for signs ... Casey Albin MD @ ... #PhysicalExam #neurology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... are not caused ... incidental CXR finding ... Diagnosis #Management #Signs ... #Symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... Increased Jaw Jerk reflex ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... Non-compressive Spinal Cord Causes ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology ... differential #algorithm
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
during bladder filling ... SUI or UUI not caused ... Incontinence #Mixed #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... depressed deep tendon reflexes ... than one after symptom ... the underlying pathophysiology ... diagnosis #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms ... diagnosis #management #neurology