46 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... mutations - Down syndrome ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... geriatrics #diagnosis #signs
Causes of Bradykinetic Movement Disorders - Differential Diagnosis Algorithm
Parkinson's Disease (TRAP):
• Resting Tremor
• Cogwheel Rigidity
• Akinesia/Bradykinesia
•
Causes of Bradykinetic ... Movement Disorders - Differential ... Algorithm Parkinson's Disease ... Bradykinesia • Falling ... • Cerebellar signs
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
suspected: • Signs ... unresponsive to treatment ... without discernable cause ... • Signs of osteoporosis ... microscopic colitis Differential
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... significant portal HTN Signs ... and hepatorenal syndrome ... obstruction) • Lack of signs ... #Diagnosis #causes
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
structural heart disease ... carotid sinus syndrome ... syncope (ruling out differential ... orthostatic vital sign ... The treatment strategy
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology ... diagnosis #management #hematology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria - Differential ... basement membrane disease ... hematuria • Signs ... of glomerular disease ... #Hematuria #Differential
Causes of Urinary Incontinence - Differential Diagnosis Algorithm
 - Transient - Easily reversible cause (DIAPPERS)
Incontinence - Differential ... Contraction - Signs ... or spinal cord disease ... , cauda equina syndrome ... #Incontinence #Differential
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... glucocorticoid treatment ... organ-specific signs ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... Carpal Tunnel Syndrome ... Cardiovascular disease ... Overproduction #diagnosis #signs