23 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... have fever - ACS ... organ damage • Treatment ... acid, Elevated Cr ... TLS #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... common • Imaging: CXR ... APML #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... complete paralysis of all ... Treatment: • Plasmapheresis ... #diagnosis #management ... #treatment #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... Imaging - CT Chest ... stimulation - Single fiber ... Gravis #diagnosis #management
Summary of meta-analysis of pharmacotherapy trials in BPD
https://www.cochrane.org/CD005652/BEHAV_psychological-therapies-borderline-personality-disorder
Meta-analyses of RCTs were undertaken for the following outcomes:
psychopathology, anger ... Guideline for the Management ... with ‘treatment ... for inclusion all ... #Pharmacology #
Pericarditis - Definition and Diagnostic Criteria
Acute Pericarditis 
 • Inflammatory pericardial syndrome to be diagnosed with
Inflammatory pericardial syndrome ... ) pericarditic chest ... CMR). ... of 4-6 weeks or longer ... diagnosis #criteria #cardiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... - Compartment syndrome ... ) • AKI: BUN/Cr ... fluid/Lactated ringers ... Differential #Diagnosis #Management
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Chest x-ray: signs ... → no signs of CXR ... : • ACE Inhibitors ... heartfailure #diagnosis #management ... #cardiology #pharmacology
Vasospastic (Prinzmetal) Angina
Definition / Epidemiology:
 • Rest angina attributed to coronary artery vasospasm.
 • Patients often
younger than other ACS ... Recurrent anginal chest ... tests in cath lab Treatment ... Prinzmetal #Angina #cardiology ... #diagnosis #management
Treatment Options for Helicobacter Pylori and Peptic Ulcer Disease

Active Helicobacter pylori—associated ulcer
1. Treat with anti—H pylori
Treatment Options ... Treatment options ... Triple Therapy (No longer ... Zollinger-EIIison syndrome ... #Management #Pharmacology