18 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
of Sickle Cell Crises ... #Diagnosis #Management ... #Hematology #SickleCell ... Manifestations #Workup ... #Algorithm #Ddxof
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... SCLE-DIL (terbinafine ... • Immunologic Workup ... Discontinuation of causal ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Manifestations: Malar rash ... versus DIL • ... • Immunologic Workup ... life-threatening • Treatment ... #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Diagnosis Algorithm ... fulminans - DIC ... deficiency Work ... #Algorithm #Causes
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... suspicion Features ... non-essential drug/HDS treatments ... for alternative causes ... #Algorithm #hepatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
NPSLE rare, Malar rash ... SCLE-DIL (terbinafine ... • Immunologic Workup ... diagnosis #treatment ... #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Edema in 70% of cases ... disease: symptomatic treatment ... Hospital of Baltimore IM ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... erythematosus [SLE ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
systemic signs (rash ... and Workup: • ... No additional workup ... CNS inflammatory cause ... #Management #Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Fibrinogen level, ↑ sIL ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... Treatment: • ... #management #treatment