13 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... extramedullary disease ... - infiltrates (anemia ... thrombocytopenia, or functional ... #Hematology #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
involved) • No leukemic ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Most common leukemia ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... marrow failure with anemia ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... cells can indicate disease ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... specific loss-of-function ... virus (EBV) • Leukemia ... #oncology #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... Ig deposition disease ... #Diagnosis #hematology ... #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... PT, aPTT(liver disease ... country), thyroid function ... (CVID, WAS), (neurologic ... changes), high MCV anemia
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... Tissue damage • Leukemia ... • Autoimmune diseases ... #differential # ... #pathophysiology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... (-) hemolytic anemia ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Myeloproliferative Disease ... blood count with differential ... #oncology