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diagnosis hematology leukemia cll lymphocytic management pharmacology algorithm anthracycline aplastic cardiology cardiotoxicity differential dyspnea hemeonc her2 malignancy mds myelodysplasia myelodysplastic
Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion
Treatment Related: - Chemotherapy ... - Cytopenias (anemia ... differential #diagnosis #oncology ... #cancer #malignancy
Testicular Cancer - Treatment Related Toxicities Bleomycin, Cisplatin, Etoposide, lfosfamide Tinnitus & Hearing Loss Neurotoxicity Pulmonary Fibrosis Hypotension Nephrotoxicity Skin Hyperpigmentation Hemorrhagic Cystitis Myelosuppression Peripheral Neuropathy Ashley
Testicular Cancer ... #Testicular #Cancer ... #chemotherapy # ... toxicity #toxicology ... #pharmacology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... 5) Symptoms of anemia ... benefit of immediate chemotherapy ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... specific loss-of-function ... Cytotoxic drugs/Chemotherapy ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... - infiltrates (anemia ... thrombocytopenia, or functional ... lymphoid organs When Cancer ... Leukemia #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Leukemia - Summary Cancer ... • Neutropenia, anemia ... leukemia #CLL #Chronic ... diagnosis #workup #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Aplastic Anemia ... Marrow Failure • Chronic ... ) • Intensive chemotherapy ... diagnosis #hematology #oncology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
ventricular ejection fraction ... Cardiotoxicity #cardiology #oncology ... #pharmacology #toxicity ... #chemotherapy
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