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Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion - Malignant pericardial effusion - Lung metastases Treatment Related: - Chemotherapy pneumonitis - Cardiomyopathy (anthracycline) - Hemorrhagic myocarditis (cyclophosphamide) - Coronary Vasospasm (cepecitabine) - Radiation pneumonitis - Radiation induced disease of: - Heart valves - Pericardium - Coronary arteries - Conduction system - Therapy-related malignancy - Cytopenias (anemia) Changes in Pre-Test Probability: - Immunosuppression —> atypical bugs - Hypercoagulable -> PE Based On: https://www.nejm.org/doi/full/10.10 #dyspnea #algorithm #differential #diagnosis #oncology #cancer #malignancy