12 results
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... - Differential Diagnosis ... Cardio-pulmonary disease • Anemia ... Myopathy - Proximal muscle ... Duchenne Muscular Dystrophy
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... heavy metals), Critical ... Neuromuscular junction ... aminoglycosides) • Muscles ... #differential #diagnosis
Gowers' Sign on Physical Exam

Caused by proximal muscle weakness typically seen in muscular dystrophy

#Gowers #Sign #PhysicalExam
Physical Exam Caused ... by proximal muscle ... PhysicalExam #neurology #clinical ... #video #pediatrics ... #muscular #dystrophy
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... decline in mental function ... Constipation • Muscle ... #emergencies #oncology ... #differential #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
specific loss-of-function ... Clinical Presentation ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... immobility • Critical ... ): • PROXIMAL MUSCLE ... - Muscular dystrophy ... #differential #diagnosis
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
blocks receptor function ... in diminished muscle ... Respiratory muscles ... syndrome - Myotonic dystrophy ... myasthenia Diagnosis
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
workup 1) Clinical ... Alzheimer - 1st cause ... - Progressive amnesia ... impaired executive functions ... #Geriatrics #Workup
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... severe mobility/functional ... • Pernicious anemia ... Hypotonia - Pain (muscle
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Pathogenesis and clinical ... SCM & digastric muscles ... hearing loss, nausea ... signs #symptoms #diagnosis ... #otology