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diagnosis treatment activetb betadglucan galactomannan infectiousdiseases latenttb tb tuberculosis workup abscess aspergillus biomarkers bloodculture causes cd4 chest comparison ct cxr
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
fastidious bacteria or fungi ... antimicrobials, clinical ... Tropheryma whipplei, Fungi ... bacteria) and 18S ( fungi ... Endocarditis #diagnosis #differential
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Pulmonary Infections ... > 200: Endemic fungi ... Aspergillus spp, Endemic fungi ... failure, COPD, Lung ... diagnosis #evaluation #differential
Miliary Pattern - Chest Radiology • Miliary opacities are scattered, small (1 -4 mm) nodules •
throughout the lungs ... Opacities: • Infectious ... - Endemic fungi ... #diagnosis #pulmonary ... #CXR #clinical
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
component of many fungi ... infection (IFI) ... cut-offs defined in clinical ... BAL GM does not differentiate ... closely related fungi
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... (NTM) • Fungal ... • Progressive lung ... characteristic features Clinical ... TB #Diagnosis #Management
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... Lung Abscess - Clinical ... Prevotella • Fungal ... #Abscess #pulmonary ... #differential #
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... (NTM) • Fungal ... • Progressive lung ... characteristic features Clinical ... TB #Diagnosis #Management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
has five major clinical ... stain of clinical ... change in the lungs ... nails, bronchi, lungs ... #Diagnosis #Management
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
component of many fungi ... surfaces, Albumin, Infections ... in BAL does not differentiate ... result in + as long ... closely related fungi
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