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Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Maintenance: 10 g ... intervals in 5-g ... QoD to 15 g QD ... of aspiration #Potassium
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
) MECHANISM: Potassium ... DOSING: 8.4 g ... Increase by 8.4 g ... week, up to 25.2 g ... patiromer) is a potassium
Potassium Electrolyte Repletion If patient also has hypomagnesemia, replete magnesium before repleting potassium Oral: • Pills (ask pharmacy
Potassium Electrolyte ... before repleting potassium ... Oral: • Pills (ask ... SatyaPatelMD #Potassium
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... ratio < 15 mEq/g ... ratio > 15 mEq/g ... #differential #potassium
Checklist Approach to Hypokalemia Consider risk factors for arrhythmia: - EKG changes (especially QT prolongation) - Digoxin
incongruous with clinical ... safely, whereas potassium ... Enteral potassium ... Intravenous potassium ... Internet Book of Critical
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
pernicious anemia) • G-CSF ... nephrology #low #potassium
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
the basis of the potassium-to-creatinine ... K+ <13 mEq K+/g ... K+ >13 mEq K+/g ... hypokalemia #urine #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• Recent IV potassium ... • Penicillin G ... diagnosis #causes #potassium
MAGIC DR – a handy mnemonic used to remember the potential causes of a cerebral ring
A – Abscess G ... eg. tumefactive MS
Emergent Hyperkalemia Treatment Algorithm ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Give 25 g ... 200 mg/dL or 50 g ... treatment Remove potassium
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