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diagnosis hematology oncology syndrome chronic cll differentiation erythematosus gravis immune inflammatory iris leukemia lupus lymphocytic myasthenia neurology reconstitution systemic workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... initiation • Differential ... Diagnosis: Infection ... #diagnosis #management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... life-threatening Differential ... Miller Fischer and PCB ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (SCLE ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... La, anti-Jo-1, SCL
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... weeks without infection ... microglobulin Treatment ... Transform to DLBCL, PML ... workup #oncology #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
six months of treatment ... leukoencephalopathy (PML ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential ... #Diagnosis #Management
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