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Celiac disease is an immune-mediated, multisystem disorder that affects genetically susceptible individuals who are exposed to
herpetiformis #gliadin
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
IgG deamidated gliadin
Celiac Disease - Diagnosis Algorithm
IgA TTG has high sensitivity and specificity of ~ 98% and is
IgG deamidated gliadin