24 results
Validation of the Step-By-Step Approach to Febrile Infants

#Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
#Diagnosis #Management ... #Pediatrics #Peds ... StepByStep #Algorithm #LP ... #Antibiotics #Risk ... Stratification #Fever
“Step by Step” – the new kid on the block – aims to risk stratify this
serious bacterial infections ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile ... #Algorithm #LP
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
92.0% and 46.9% #Diagnosis ... #EBM #Management ... #Pediatrics #Peds ... StepByStep #Algorithm #LP ... Stratification #Fever
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... : • Infectious ... Coxsackie, CMV, EBV ... Prunelle Getten ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... • Autoimmune diseases ... Adult-onset Still disease ... #management #treatment ... #summary #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... - Pel-Ebstein fever ... Etiology: - Infections ... Differential Diagnosis ... Malignancies (eg CML
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... age, however the disease ... following: • Fever ... #management #treatment ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... procedures - Infection ... l MD SOAP) - Risks ... changes), high MCV ... When do you do a BM
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Headaches, bone pain, fever ... Lymphadenopathy • HSM • Fevers ... #Leukemia #Hematology ... #Oncology #Diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Periodic fever ... SLE], AOSD) • Infection ... 5000 to 10,000 ng/mL ... Activation #Syndrome #Diagnosis ... #Management #Hematology