12 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... #Workup #hematology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Disorder (HAND) ... Encephalopathy ... reversible • HAND ... patients #HAND ... #Neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... should be based on clinical ... Antimicrobial treatment ... #HIV #CNS #Infections ... diagnosis #AIDS
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... to right with bands ... #differential # ... #WBC #CBC #hematology ... #pathophysiology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Clinical Presentation ... Mycoplasma, EBV, HIV ... younger pts) Differential ... Disorders Such As ... #hematology #diagnosis
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
) - Diagnosis and ... ♀, ↑Age, ESRD Pathophysiology ... : Confirmatory test ... #Management #Treatment ... #Hematology #HemeOnc
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
- Diagnosis and ... other causes of neurologic ... Precipitants: Infection ... #Grading #Classification ... #treatment #hepatology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... response preceding infection ... Campylobacter jejuni - HIV ... Paresthesias: Hands ... #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Posterior Reversible Encephalopathy ... may precede the neurologic ... Etiology: • Pathophysiology ... edema visualized as ... Reversible course Differential
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... vs infection vs ... variably: On one hand ... them, but urgent rheumatology