19 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver Disease ... : Primary Biliary ... Cirrhosis vs Primary ... pathophysiology #pbc ... #psc #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... of autoimmune disease ... #PBC #Primary ... Diagnosis #Algorithm #hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgM) (e.g. primary ... cold agglutin disease ... • Intrinsic RBC ... e.g. sickle cell disease ... differential #diagnosis #hematology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... relative with PBC ... #Primary #Biliary ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... Cirrhosis (PBC) ... cholestasis → Cirrhosis ... #Biliary #Cirrhosis ... diagnosis #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
: > 2 • NASH, ... hepatitis: < 1 • Cirrhosis ... (hemolysis, bleeding ... (hemolysis) • ... diagnosis #algorithm #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... management. ... #Primary #Sclerosing ... Cholangitis #diagnosis #management ... #summary #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... underlying liver disease ... Liver #Failure #Cirrhosis ... #Hepatology #gastroenterology ... #management #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
15% of AIHA Primary ... Diagnosis: • hemolytic ... Blood smear - RBC ... #hemolytic #anemia ... #hematology #diagnosis
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
Liver Consult Primer ... Gl History - Cirrhosis ... Chronic liver disease ... Calling #Referral #Hepatology ... #Gastroenterology