7 results
Kaposi Sarcoma Herpes Virus (KSHV)

By Dr. Sara Dong @swinndong via #IDFellowCase
#ID  #Infectious Diseases  #Infections
#Differential
Herpes Virus (KSHV ... Ddx #Diagnosis #KSHV ... #HHV #lymphoproliferative ... #KICS
KSHV Inflammatory Cytokine Syndrome (KICS)

By Dr. Sara Dong @swinndong  via #IDFellowCase
#ID  #Infectious Diseases
KSHV Inflammatory ... Cytokine Syndrome (KICS ... Ddx #Diagnosis #KSHV ... #HHV #KICS #Kaposi
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... • Association HIV ... Light chain: - HHV8 ... de Fremont #HHV8 ... comparison #diagnosis #kshv
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory ... Cytokine Syndrome (KICS ... Definition for KICS ... ID_fellows #KICS ... diagnosis #management #hhv8
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Preventing and Treating HHV ... activity against HHV ... recommended for KS treatment ... adjunctive therapy #HHV8 ... IDSA #Prevention #Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Virus (EBV, CMV, HHV8 ... Unknown cause Treatment ... diagnosis #management #treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
six months of treatment ... Kaposi sarcoma, HHV8 ... Poor adherence to treatment ... by delaying ART treatment ... eight weeks) after treatment