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management oncology syndrome disease infectiousdiseases workup chronic cll comparison endocarditis hodgkins leukemia lymphocytic signs symptoms adultonset agglutinin aids algorithm ana
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- Comparison ... e.g., HIV), EBV infection ... • Clinical features ... #differential # ... hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... accumulation of clinical ... , B-cell lymphoma ... , Infection under ... #summary #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... fraction < 20% Differential ... Infectious: Mycoplasma ... hepatitis • Pulmonary ... #treatment #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hypogammaglobulinemia -> increased infection ... to 8 years Clinical ... with CVID have a history ... • Nodules • Lymphoid ... hypogammaglobulinemia #immunology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... procedures - Infection ... (CVID, WAS), (neurologic ... #Workup #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of EBV infection ... - Clinical Presentation ... number of sites of disease ... Treatment • Early ... #hematology #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Due to Viral infection ... Polyclonal - Viral Infection ... Clinical Presentation ... younger pts) Differential ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytes • Median ... immunophenotype Clinical ... Complications: 1) Infection ... to large cell lymphoma ... Leukemia #oncology #hematology
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
• Infection with ... requires special media ... ) • Infection with ... Diseases Fellows ... #differential #
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
: Serial negative ... valve pathology, History ... large infarct - Infectious ... Diseases Fellows ... #Endocarditis #comparison
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