13 results
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
requires special media ... antimicrobials, clinical ... BCNIE Diagnostic ... Diseases Fellows ... #differential #
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Clarkson’s Disease ... published cases, Median ... filling +++ (risk of pulmonary ... , treatment of infections ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Renal Syndromes ... confirm DAH, r/o infection ... #Renal #Syndromes ... diagnosis #management
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
: • Syndrome of ... History of immunosuppressive ... Disease: Clinical ... #differential # ... diagnosis #infectiousdiseases
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... and renal abnormalities ... + MPO-ANCA MEDIUM ... to exclude are infections ... #diagnosis #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... Anaphylaxis, Acute Renal ... #management #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... and renal abnormalities ... primary condition MEDIUM ... #Diagnosis #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Malignancy • Infections ... thrombophlebitis, pulmonary ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Histo ... salivary ducts Clinical ... : • 10%-15% Pulmonary ... #Rheumatology # ... Diagnosis #Management