24 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Peripheral edema, Disease-specific ... Diagnosis for Pulmonary ... vasculitis, Behcet disease ... Goodpasture's Disease ... diagnosis #nephrology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... cancers • Systemic diseases ... autoinflammatory diseases ... #diagnosis #management ... #treatment #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... confirm DAH, r/o infection ... diagnosis #management ... #treatment
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
HIV/AIDS, CGD) Clinical ... presentations: • Pulmonary ... positive with Histo ... Diseases Fellows ... #Management #treatment
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Clarkson’s Disease ... - To treat disease ... - To prevent disease ... #Clarksons #Disease ... #diagnosis #management
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
• Chronic lung disease ... History of immunosuppressive ... Disease: Clinical ... #differential # ... diagnosis #infectiousdiseases
Fusarium Infections
Acquired through:
1. Inhalation of airborne conidia > germinates > blood > disseminated
2. Trauma (implantation with
Refractory FUO, Sino-pulmonary ... , Disseminated disease ... for disseminated disease ... Diseases Fellows ... #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Medium and large ... ) Differential Diagnosis ... Arthritis, AS Treatment ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
rheumatic diseases ... atherosclerotic disease ... most important diseases ... (GRANULOMATOUS DISEASE ... #Diagnosis #Rheumatology