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diagnosis classification management vasculitis acidosis ana antibodies antinuclear apml causes chest clinical comparison ct differentiation elevation eosinophilia eosinophilic hematology lactate
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Renal Syndromes ... , anti-CCP • CXR ... #Renal #Syndrome ... #differential #
Miliary Pattern - Chest Radiology • Miliary opacities are scattered, small (1 -4 mm) nodules •
hematogenous spread of a disease ... Endemic fungi: Histo ... thyroid, melanoma, renal ... #diagnosis #pulmonary ... #CXR #clinical
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Renal Syndromes ... confirm DAH, r/o infection ... • IF staining patterns ... #Renal #Syndromes
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
microscopy and serial ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... #rheumatology # ... diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... and renal abnormalities ... + MPO-ANCA MEDIUM ... to exclude are infections ... #diagnosis #rheumatology
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
arthralgias, CV, renal ... Hypereosinophilic Syndrome ... , CNS, skin • Infectious ... #pulmonary #differential ... #diagnosis #comparison
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... and renal abnormalities ... primary condition MEDIUM ... white and gray matter ... #Diagnosis #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
common • Imaging: CXR ... - pulmonary opacities ... initiation • Differential ... Diagnosis: Infection ... Anaphylaxis, Acute Renal
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
presentations and disease ... patient’s complete medical ... history - conduct ... output - Acute pulmonary ... - Compartment syndrome
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